What are Enzymes?

Enzyme molecules break down endocannabinoids after they’ve completed their function. The most pertinent enzymes to know are fatty acid amide hydrolase and monoacylglycerol acid lipase.

Together, these three components—endocannabinoids, receptors, and enzymes—help ensure your endocannabinoid system achieves homeostasis in your body. And when a CBD sublingual comes into the picture, it interacts with this complex network to help accomplish that homeostasis. 

This process starts when you put a few drops of a CBD sublingual underneath your tongue. While the CBD oil is sitting there, your mucous membrane and blood vessels are absorbing the formula into your bloodstream. 

 However, once your body absorbs the CBD sublingual, the formula binds with the CB1 receptors in your brain and the CB2 receptors that run throughout your entire body. After binding together, the CBD oil provides the relief that you need. 

 This process is somewhat different than what other delivery methods offer. While every reliable CBD product will interact with your endocannabinoid system, the way that happens will vary. For example, CBD sublinguals interact with your body differently than CBD capsules, CBD inhalers, and CBD topicals.

Are there CBD sublingual oil side effects?

Generally, CBD sublinguals will not provide any adverse side effects. In fact, one recent study found that the “often described favorable safety profile of CBD in humans was confirmed.”

However, if you encounter a low-quality or fake CBD product with harmful ingredients, you may experience some adverse reactions. What’s also important to note is that you might notice side effects if you take too much CBD at one time. 

For example, the study mentioned above also suggests that CBD oil can trigger the following side effects: 

• Tiredness
• Diarrhea
• Changes in appetite 
• Changes in weight 

While these side effects are minimal, it’s still possible to encounter some sort of adverse reaction if you don’t use the right CBD sublingual and dosage. It’s also important to remember that combining CBD oil with certain medications may lead to adverse side effects.

For instance, maybe you take a medication that warns against eating grapefruit because it could activate the P450 liver enzyme. If this is the case, you shouldn’t use a CBD sublingual or a CBD product at all unless it’s under a doctor’s supervision. The CBD could impact the medication’s effect and make it a toxic substance in your system. 

As with all remedies, it’s helpful to consult your doctor if you’re taking medications and are unsure how CBD will interact with them. You want to focus on helping your body, not harming it. And you may need a physician’s advice to ensure you do that.

What are CBD sublingual oil benefits?

If you speak with your physician and realize that CBD sublinguals are a great option for your health and wellbeing, you may experience a host of therapeutic benefits from using them.  Here are three of a CBD sublingual’s benefits.

CBD sublingual oil may soothe anxiety

One of CBD’s primary uses is for relieving stress and anxiety, and research indicates that CBD may actually help with this. 

Researchers published a study in Neurotherapeutics that suggests CBD has potent anxiety-relieving effects on animals. Experts suggest this response could correlate with CBD’s impact on the brain. But to get a better understanding, researchers conducted a few studies on humans. 

In 2019, researchers published a study in the Brazilian Journal of Psychiatry. The study examined 57 men who received either CBD oil or a placebo drug before they had a public speaking event. 

The researchers analyzed the participants’ blood pressure, heart rate, and other factors to determine their anxiety level. And they also used the Visual Analog Mood Scales, which test people’s mood states. 

Based on the study’s results, the men who received 300 mg of CBD had less anxiety than the ones who took a placebo. Researchers still need to conduct and publish more studies to continue to confirm CBD’s anxiety-relieving effects, but so far, the results are promising.

CBD sublingual oil may decrease nerve pain

What’s also exciting is that studies report that CBD sublingual may help reduce nerve pain.

In an animal study that researchers published in the Journal of Experimental Medicine, scientists provided their findings after giving rats an oral dose and spinal injection of CBD. 

The researchers had given the rats inflammatory chemicals in their hind feet before providing the dose of CBD. And they discovered that the CBD decreased the neuropathic pain and inflammation that the rats were experiencing.

CBD sublingual oil may boost heart health

The potential benefits of CBD sublingual don’t stop at reducing anxiety and nerve pain.

Studies also suggest that it can boost heart health by alleviating hypertension. For example, in 2017, researchers published a study in JCI Insight. 

For the study, researchers gave nine healthy men either 600 mg of CBD or 600 mg of a placebo. After examining the results, the researchers learned that the men who took the 600 mg of CBD sublingual had lower blood pressure. What’s even more interesting is that the men showcased these results before and after they were exposed to stressful situations, including extreme cold and exercise. 

While scientists are still conducting more research, current studies suggest that CBD sublingual may possess therapeutic effects. With a high-quality product and the proper dosage, CBD’s relieving properties may increase your quality of life.

What is a CBD sublingual dosage?

After you buy and receive your CBD sublingual, you need to determine the best dosage before you use it. The company you bought the remedy from should indicate the best dose for the product on the label or website.

But those recommendations are just guidelines to help you get started. Several factors will determine how much CBD sublingual you should take, including your environment, diet, weight, genetics, metabolism, and reason for using the remedy. 

A great rule of thumb is to take the lowest recommended amount and then increase your serving size if you want to experience more relief. You should also increase your CBD sublingual dosage every 3-4 weeks to better understand how the previous one impacted you.

Having a journal to write down your results will help keep you organized during this process. And it will give you a frame of reference, so you can tailor your CBD sublingual dosage to the specific effect you want to achieve.

How do I use CBD sublingual oil?

Once you know your CBD sublingual dosage, you’re finally ready to try it. Administering CBD oil sublingually is easy, quick, and painless. Here are the few steps that you should take to use CBD sublingual:

• Shake the bottle well before you open it. 

• Put the recommended number of drops underneath your tongue. 

• Hold the drops underneath your tongue for 60 seconds. 

• Swallow the formula after 60 seconds.

Some CBD companies will suggest how often you should take your CBD sublingual. These recommendations are to ensure you encounter the best results, and they will typically differ depending on the product. 

For example, with Kat’s Naturals’ Relax, we recommend that you use it when you’re stressed, ready to go to bed, or every 4 to 6 hours. However, with Kat’s Naturals’ Naked, we suggest that you use it 2 to 4 times per day for 6 to 8 weeks. Then, you should lower your frequency to 1 to 2 times per day after that.

If your physician suggests a different frequency, you should listen to that information as well. Your doctor should have insight into the best times to take CBD sublingual, and that advice is essential to heed.

What is CBD sublingual bioavailability?

Once you’ve taken your CBD sublingual, you want to know that it’s going to work, especially if you bought it from a credible company. This is when you might consider bioavailability.

While CBD provides therapeutic relief, it won’t offer you anything if it doesn’t absorb well into your bloodstream. This potential pitfall is why bioavailability is so critical. It’s what helps determine if you experience relief.  

To put it in formal terms, bioavailability centers on how much something gets absorbed into your bloodstream. Depending on the CBD delivery method that you choose, the bioavailability will vary. 

For example, instead of buying a CBD sublingual, maybe you purchased an oral CBD product like a CBD beverage, capsule, or edible. If that’s the case, with this delivery method, the bioavailability rate will be lower than others.

Research suggests that the bioavailability of oral CBD is anywhere between 10% to 20%, but some studies report even lower numbers like 6%. The reason for these low numbers centers on the way oral CBD travels into your bloodstream. 

When you ingest it, the CBD has to pass through and break down in your digestive system first. Then, it finally enters your bloodstream. However, this journey is not always linear. Sometimes, the CBD gets lost in your liver or digestive tract, decreasing the amount of CBD that you absorb into your bloodstream.  

This information doesn’t mean that oral CBD products are bad. In fact, Kat’s Naturals’ oral CBD remedies—like our professional CBD capsules—have almost a 99% bioavailability rate because we use specific organic ingredients to enhance how much CBD your body absorbs. 

But with CBD sublinguals, the bioavailability is naturally higher. Research suggests that CBD sublingual has a bioavailability rate of 13% to 19%. However, some studies even peg the bioavailability rate at 35%. These higher bioavailability percentages are a result of the way you use CBD sublinguals. 

This delivery method requires you to hold CBD oil underneath your tongue, allowing the formula to immediately absorb into your mucous membrane. From there, the CBD quickly travels into your bloodstream, releasing a potent therapeutic effect once it’s there.

With a credible CBD sublingual, you can rest assured that you will feel relief. You just have to wait for the effect to kick in, which usually happens within 10-15 minutes.

Are essential oils in CBD sublingual oils?

When you ingest a CBD sublingual, you might notice that it has a sweet or citrusy taste. This flavoring is a result of essential oils.

At Kat’s Naturals, we love to include small amounts of sustainably harvested essential oils in our CBD sublinguals. And when appropriately added, it’s safe to include some essential oils in CBD sublinguals. What’s even better is that essential oils offer therapeutic relief.

Essentials oils effectively capture and provide a plant’s scent and flavoring, adding another soothing element to CBD sublinguals. There are currently more than 90 different essential oils that people commonly use, and each of them offers its own unique therapeutic properties. In fact, studies suggest that essential oils may alleviate some health concerns.

1. Essential oils may reduce anxiety

Research indicates that just smelling essential oils can help promote peace and tranquility to decrease anxiety. 

For example, researchers examined 40 male volunteers who were broken up into different groups. One group inhaled sweet orange essential oil while the others smelled “controlled aromas” like water and tea tree essential oil. 

Immediately after inhalation, the researchers analyzed the anxiety levels in each test group. And they found that the men who smelled the sweet orange essential oil experienced a lack of state-anxiety and subjective tension. These results led the researchers to believe that the sweet orange essential oil had anxiolytic properties. 

This reported benefit is a primary reason why wild orange essential oil is in our THC free CBD sublingual called Relax. The addition of this sustainability harvested ingredient helps relieve stress and tension.

2. Essential oils may relieve headaches

Studies also report that essential oils may help relieve headaches. 

For one study that researchers published in the National Library of Medicine, scientists applied peppermint oil, eucalyptus oil, and ethanol onto 32 healthy participants’ foreheads and temples. Afterward, the researchers noticed that the combination increased cognitive performance and helped relax the participants’ muscles and mental state. 

Another study also produced interesting results. Researchers recently analyzed 164 headache attacks in 41 patients of both sexes who were 18-65 years old. These participants suffered from tension-type headaches, which is in accordance with the International Headache Society’s classification. 

The researchers examined four headache attacks per patient and gave them a capsule and oil preparation that included peppermint oil. The researchers rubbed the oil across the participants’ forehead and temples every 15 to 30 minutes. 

And they noticed that a “10% peppermint oil in ethanol solution significantly reduced the clinical headache intensity” after 15 minutes. This decrease in pain intensity continued to decline throughout the one hour observation period. 

Given peppermint oil’s reported benefits, you’ll find it in three of our products. At Kat’s Naturals, we use this therapeutic essential oil in Heal, Restore, and Balance.

3. Essentials oils may improve sleep

Researchers are also finding that essential oils might help improve sleep.

For example, scientists examined 15 different studies. And they discovered that the majority of research indicated that smelling essential oils, and lavender oil, in particular, had significant effects on sleep quality.

What’s also interesting is that lavender essential oil also seemed to help postpartum women sleep better. Scientists analyzed 158 mothers who were still in the postpartum stage. Some of the participants inhaled lavender essential oil every night before going to bed. 

The fragrance was put on cotton balls, which stayed in a container. And after sniffing the cotton balls, the mothers placed the container near their pillow until they woke up the next morning. The women followed this procedure for eight weeks. 

Then, afterward, the researchers examined the results. Unsurprisingly, they noticed that the women who smelled the lavender essential oil experienced significant improvement in their sleep quality.