Media Summary: Review of the regulatory networks that can be inferred by ChIP-seq assays on DNA--binding transcription factors. An overview of enrichment analyses to identify significant overlap between gene lists from e.g. CRISPR-Cas9 screens, and gene ... Introduction to the reverse genetics approaches (siRNA, antisense oligos) to functional genomics.
2022 Mcb 182 Lecture 4 - Detailed Analysis & Overview
Review of the regulatory networks that can be inferred by ChIP-seq assays on DNA--binding transcription factors. An overview of enrichment analyses to identify significant overlap between gene lists from e.g. CRISPR-Cas9 screens, and gene ... Introduction to the reverse genetics approaches (siRNA, antisense oligos) to functional genomics. Introduction to forward genetics approaches to functional genomics. Considerations about how to choose between 3C/4C/Hi-C, and also a brief discussion of how Hi-C can be used for genome ... Introduction to the concept of absolute entropy and information content of DNA sequences
