Media Summary: An overview of enrichment analyses to identify significant overlap between gene lists from e.g. CRISPR-Cas9 screens, and gene ... Review of the regulatory networks that can be inferred by ChIP-seq assays on DNA--binding transcription factors. Basic overview of DNA sequencing and its applications
Mcb 182 Lecture 4 2 - Detailed Analysis & Overview
An overview of enrichment analyses to identify significant overlap between gene lists from e.g. CRISPR-Cas9 screens, and gene ... Review of the regulatory networks that can be inferred by ChIP-seq assays on DNA--binding transcription factors. Basic overview of DNA sequencing and its applications Introduction to forward genetics approaches to functional genomics. Introduction to the concept of absolute entropy and information content of DNA sequences The structure of the gene ontology hierarchy and database
A brief introduction to the genetics of complex traits, and how they differ from e.g. Mendelian disorder genetics. Introduction to the chromatin conformation capture assays, including 3C and 4C. Introduction to histone modifications as an epigenetic mark, as well as the ChIP-seq and CUT&RUN technologies to assay them.
