Media Summary: A video demonstrating chromosome organization by A new video shows how DNA stays packed up but doesn't get jumbled, which could have implications for cancer research. The human genome is two meters long but fits inside the microscopic nucleus of a cell. How does it do this? Our work suggests ...
Loop Extrusion Waltz - Detailed Analysis & Overview
A video demonstrating chromosome organization by A new video shows how DNA stays packed up but doesn't get jumbled, which could have implications for cancer research. The human genome is two meters long but fits inside the microscopic nucleus of a cell. How does it do this? Our work suggests ... Inside the nucleus, DNA is packed in highly complex structures that help to control which genes are on and off each time. Representative simulation of chromosome compaction by Prophase chromosome compaction and segregation by loop extrusion: 3. Sister chromatid segregation
from Fudenberg, Imakaev et al, Formation of Chromosomal Domains by Professor Alt described the mechanism of cohesin-mediated chromatin For more information see: "A pathway for mitotic chromosome formation", J. Gibcus, K. Samejima and A. Goloborodko et. al., ...
