Media Summary: Fragment-based molecular replacement involves the use of very accurate yet incomplete search models. In this context, we have ... Model refinement is a key step in crystallographic structure solution, allowing an atomic model to be optimised to best explain the ... Many biologists are now routinely seeking to determine the structure of their proteins of choice, illustrating the importance of this ...
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Fragment-based molecular replacement involves the use of very accurate yet incomplete search models. In this context, we have ... Model refinement is a key step in crystallographic structure solution, allowing an atomic model to be optimised to best explain the ... Many biologists are now routinely seeking to determine the structure of their proteins of choice, illustrating the importance of this ... The conventional approach to identifying search models in molecular replacement (MR) is to utilise the sequence of the target to ... I am going to interpret this title as allowing me to look towards the future as well muse about the past. Essentially all ... Likelihood-based methods have come to play a prominent role in macromolecular crystallography. For molecular replacement ...
Micro-electron diffraction (MicroED), a cryo-electron diffraction method, has proven successful in determining the atomic structures ... Topic: MOSFLM and FRIENDS: Data Processing in the The ever-increasing number of structures deposited in the Protein Data Bank constantly improves our ability to data-mine protein ... The ARP/wARP software continues to provide a range of advancing functionalities to build models of macromolecular structures ...
