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Unlike anandamide, studies suggest that 2-AG is the primary endocannabinoid involved in retrograde signaling in the brain and the true natural ligand for cannabinoid receptors.
With this process, cultivators embed seeds into foam that’s stuffed into small pots that hold a plant’s root mass and stem in place. With light and a mist infused with nutrients, the plants receive nourishment.
Afterward, extractors strain the flower and place the leftover liquid over a low heat source to remove the alcohol while preserving the cannabinoids.
It’s naturally produced in the body and interacts with the cannabinoid receptors in the endocannabinoid system.
Also called N-arachidonoylethanolamine (AEA), this molecule is not only a cannabinoid-receptor binding agent but a neurotransmitter that sends signals to the cannabinoid receptors that are located throughout the body. By binding with receptors, anandamide affects various functions, including fertility, mood fluctuation, appetite, and pain management.
With this delivery method, users should apply CBD balms directly to the surface of their skin. CBD balms are great for pain management and restoration.
When you put a CBD bath bomb into the water, the sodium bicarbonate in the bomb releases carbon dioxide gas by interacting with the citric acid. For example, think of Alka-Seltzer tablets in water. When the CBD bath bomb breaks down, it should release soothing fragrances, colorants, and ingredients that moisturize the skin.
The more CBD that enters the bloodstream, the more potent the CBD will be. Experiencing higher levels of CBD will depend on the type of product that a user buys and how that user takes it. Currently, studies suggest that ingesting CBD leads to a much lower bioavailability rate than inhaling CBD. However, the effects of ingestion are longer.
Even though broad-spectrum CBD products are THC-free, they still deliver the entourage effect. This remedy is excellent for CBD users who want drug test safe products.
Cannabaceae is part of the hemp family (order Rosales). Rosales is the rose order of dicotyledonous flowering plants. It features 9 families, 216 genera, and more than 7,700 species.
A non-intoxicating cannabinoid, CBC is considered one of the “big six” cannabinoids in medical research. Similar to THC and CBD, CBC also derives from cannabigerolic acid (CBGA). Studies suggest that CBC may help with pain, inflammation, depression, and more.
A non-intoxicating compound, CBCA derives when CBGA and breaks down to produce cannabichromene (CBC).
When cannabis flower has reached almost full maturity, CBCA is one of the cannabinoids that appear. Unlike other molecules in cannabis, CBCA is not present in high quantities in any Cannabis sativa strain. Not many studies exist on CBCA, but research suggests the cannabinoid may help relieve bacterial infections.
In cannabis strains, CBCV exists in smaller amounts than THC and CBD. Research is limited on CBCV. However, because its molecular structure is similar to CBC, CBCV may have the same effects as CBC.
This molecule is the precursor to cannabichromevarin (CBCV). Not much research has been done on CBCVA, but some industry experts and users believe it may help regulate sleep, appetite, and mood.
CBD is a cannabinoid that’s present in the cannabis and hemp plant when CBDA breaks down. There are many products with “CBD” attached to it, but not all of these products are created equal. Research suggests that CBD may help with anxiety, depression, inflammation, heart health, skin health, chronic pain, nausea, and more.
The ECS is a biological system composed of neurotransmitters that bind to cannabinoid receptors CB1 and CB2, which are expressed throughout the vertebrate central nervous system and peripheral nervous system. CBD helps modulate and regulate the firing of the CB1 and CB2 receptors.
Sublingually: We advise taking 3-5 drops of CBD oil, which is a mid-range amount for most individuals. Put the CBD drops underneath your tongue and keep them there for 60 seconds. The effects of the CBD oil will work in 15 minutes and last 4-6 hours.
Inhale: We recommend that you inhale 2-3 puffs of CBD, which is a medium-size amount for most individuals. When you inhale, hold your breath for 5 seconds. This method works very fast and lasts about 2-4 hours.
Topically: Rub a small amount of CBD onto the affected area of your body — there’s no need to use large amounts. This method works very fast and lasts about 2-4 hours.
Edibles: We suggest eating one chocolate square or 1 tsp. of edible hemp. It takes around 30-45 minutes for the edible to take effect, but it lasts up to 8 hours.
This molecule derives from CBGA. Over time, CBDA converts to CBD when extractors apply heat to the cannabinoid. Research suggests that CBDA reduces inflammation, helps control nausea, decreases depression, and affects levels of serotonin.
This molecule is present in the hemp plant, and it’s similar to CBD in its structure. This cannabinoid will not provide a psychoactive effect. Studies suggest that CBDV has anti-epileptic properties and may help with neurobehavioral conditions, memory, muscular dystrophy, inflammation, and nausea.
It’s the carboxylic acid precursor of cannabidivarin (CBDV) and is non-psychoactive. Studies suggest that CBDVA may have anticonvulsant properties, but research on its therapeutic benefits is still ongoing.
Unlike THC and CBD, CBG presents itself in low levels in most strains. In fact, CBG usually makes up less than 1% of cannabis strains. CBG is a minor cannabinoid, and it’s present when CBGA breaks down.
Studies suggest that CBG may help relieve glaucoma and inflammation from inflammatory bowel disease (IBD). Researchers also report that CBG may reduce bladder dysfunction disorders and fight bacterial infections.
It’s one of many minor cannabinoids in the cannabis plant, and it’s a critical compound in cannabis flower as it helps protect the plant. By triggering plant cell necrosis for natural leaf pruning, CBGA helps the cannabis plant increase energy directed toward the flower.
Known as the “mother of all cannabinoids,” CBGA is also the acid precursor to cannabigerol (CBG) and breaks down to produce three major molecules, such as cannabidiolic acid (CBDA), cannabichromenic acid (CBCA), and tetrahydrocannabinolic acid (THCA). Those cannabinoids eventually lead to CBD, CBC, and THC. Studies suggest that CBGA may help with various conditions, including cardiovascular disease and metabolic disorders.
A non-psychoactive compound, CBGV is a lesser-known cannabinoid in and Cannabis sativa plant. Researchers report that CBGV may have analgesic and anti-inflammatory properties. Studies also suggest that CBGV may help improve dry-skin conditions.
It’s the carboxylic acid precursor of cannabigerovarin (CBGV). Considered to be a “stem cell” cannabinoid, CBGVA goes through enzymatic processes to transform into the carboxylic acid precursors of varin cannabinoids such as CBDVA, THCVA, and CBCVA.
The two most notable cannabinoids are THC and CBD.
Each cannabinoid in the cannabis and hemp plant shows up in different levels. When users take cannabinoids, the molecules act on the endocannabinoid system’s receptors.
Every cannabinoid has therapeutic properties, but researchers are still studying each cannabinoid to better understand its benefits and how it works. When taking multiple cannabinoids, users experience the entourage effect, which provides a more holistic impact on the body.
They are critical components of the body’s endocannabinoid system, which helps with various physiological functions, such as memory, mood, appetite, and pain sensation.
Exogenous cannabinoids in the cannabis plant are the main molecules that trigger cannabinoid receptors. So far, researchers have discovered that the primary cannabinoid receptors are CB1 and CB2.
A non-intoxicating compound, CBN is present when THC ages. As a result, in older cannabis, CBN can exist at high levels. Users report that the cannabinoid provides a meditative feel. Research also suggests CBN may help reduce bacterial infections, protect the brain, and stimulate appetite.
Slang terms for cannabis include marijuana, skunk, Mary Jane, weed, pot, dope, grass, and reefer. In general, these slang terms refer to the high THC levels used for recreational consumption.
Because Cannabis indica contains higher concentrations of THC, it’s popular as a recreational and medicinal drug.
Commonly, cannabis oil is intended to be high in THC and low in CBD, but it can also feature a balance of the two.
Indigenous to eastern Asia, this flowering herbaceous plant has been farmed throughout recorded human history. Different parts of the plant are harvested to create marijuana products, CBD products, hemp fiber, hemp seed oil, and food products.
The three primary subtypes on the cannabinoid spectrum are full-spectrum CBD, broad-spectrum CBD, and CBD isolate.
With over 6,000 types, flavonoids are natural, nutritious compounds that assist in creating beautiful colors in plants, flowers, vegetables, and fruits to attract butterflies, bees, and birds.
They are a primary cannabinoid receptor that helps the endocannabinoid system function so that the body maintains homeostasis. CB1 receptors are mainly present in the brain, central nervous system, liver, lungs, and kidneys.
Delta-9-THC, the main intoxicating ingredient in cannabis, primarily targets CB1 receptors to deliver an effect. It agonizes CB1 receptors until it activates so that users feel THC’s therapeutic impact.
A critical cannabinoid receptor in the endocannabinoid system, CB2 receptors help the body function properly and maintain homeostasis. CB2 receptors also play a vital role in the body’s immune system and in combating inflammation.
Unlike CB1 receptors, CB2 receptors are mainly found on immune cells, which move throughout the brain and body using the bloodstream. CB2 receptors are also located in the spleen and in some liver cells and bones.
Similar to pills or tablets, CBD capsules refer to ingestible products. Unlike tablets, which are generally flat, capsules are usually cylindrical. They also consist of a dissolvable gelatin container that features a compound, like a jelly or a powder.
With a CBD concentrate, users get a higher dose of CBD in a shorter time. There are many forms of CBD concentrates, including CBD butter, CBD wax, CBD resin, CBD crumble, and CBD rosin.
To evaporate and inhale a CBD dab, users must apply the remedy to a heated plate or vaporizer.
When manufacturers develop a CBD isolate, they remove everything in the plant matter, including other beneficial cannabinoids and traces of THC. The only thing that’s left is a powder or crystalline form of CBD. With a CBD isolate, users will only experience the benefits of CBD and not the entourage effect.
CBD oil is a popular remedy, but not all are created equal.
It includes a higher concentration of CBD, making it a more popular remedy. Users only need to take small amounts of CBD wax to get a potent effect. CBD wax gets its name because it takes on a wax-like appearance and consistency once manufacturers extract and purify it.
This proof is beneficial to consumers and producers. Both parties get reassurance that a CBD remedy includes everything the product label suggests.
Consumers should always look at a Certificate of Analysis to avoid low-quality, fake, and mislabeled products. If a CBD company is reputable, it will showcase a Certificate of Analysis for each of its remedies.
Studies suggest that cesamet helps with severe nausea and vomiting.
Chlorophyll absorbs energy from light and uses that energy to convert carbon dioxide to carbohydrates.
This concept suggests that low levels of endocannabinoids may lead to ailments like fibromyalgia, migraines, and irritable bowel syndrome (IBS).
Commonly used in the past to develop beauty products and perfume, closed-loop extraction is making a comeback. Recently, extractors have started using it to make cannabis concentrates.
CO2 extraction gently draws out a plant’s therapeutic components, leading to a safe and clean oil that has a long shelf life. This extraction method is a more expensive technique, but its benefits outweigh the costs.
Usually, a cultivator is focused on plant health and soil quality.
When curing, manufacturers remove moisture from the flowers in environmental conditions that they control.
The sticky oils that result from this process are sometimes called wax. When a CBD user is dabbing a dab, the individual is inhaling a concentrated dose of CBD that gets released when heated and vaporized. Typically, CBD users who want quick therapeutic benefits prefer dabbing.
The delivery method that CBD users choose will determine how quickly a remedy works and how much of the product gets absorbed into the bloodstream. There are several types of CBD delivery methods, including tinctures, vapes, topicals, chocolates, gummies, capsules, and salves.
The laws regarding dispensaries differ by state.
The CBD dosage that a user chooses depends on their purpose for using CBD, metabolism, and their preferred delivery method.
This remedy may help with weight loss and loss of appetite in people with cancer or HIV. Common brand names of dronabinol are Marinol and Syndros.
Examples of CBD edibles are CBD-infused chocolates, gummies, capsules, baked goods, martinis, butter, and candy.
Examples of eicosanoids are endocannabinoids.
They are chemicals that the body naturally produces to interact with the endocannabinoid system and help regulate critical functions within the body. The primary purpose of endocannabinoids is to help the body maintain homeostasis. Currently, there are two known endocannabinoids: anandamide (AEA) and 2-arachidonoylglycerol (2-AG).
The endocannabinoid system is responsible for various functions, including sleep, appetite, pain, stress, fertility, and reproduction.
The primary function of this complex network is to help the body maintain homeostasis even when the environment changes. Researchers believe that hemp can help the endocannabinoid system achieve homeostasis since the plant’s phytocannabinoids interact with and activate the body’s endocannabinoids and endocannabinoid receptors.
This concept centers on the idea that a remedy with more than one cannabinoid will deliver a better effect. For example, CBD users who want a more holistic product prefer full-spectrum CBD and broad-spectrum CBD versus isolate CBD.
Volatile chemical compounds, essential oils are typically extracted so that manufacturers can use the concentrated flavors and aromas contained within a plant.
Manufacturers extract essential oils using a distillation process that involves steam. However, less common extraction methods include solvent extraction, resin tapping, and cold-pressing.
People commonly use essential oils for aromatherapy and alternative medicine. But some CBD companies include essential oils in their remedies to enhance their products’ taste and therapeutic effects.
With this method, manufacturers use cold, high-grade alcohol to gently pull the active compounds from the hemp plant’s cellulose material to develop products. Any oil that manufacturers extract is then further refined to remove all remaining traces of ethanol.
There are many ways to extract CBD from the hemp plant, including CO2 extraction and cold ethanol extraction.
With this legislation, people can legally purchase CBD products in all 50 states.
Under the Farm Bill, industrial hemp—where CBD products come from— must contain less than .3 % THC. Federal and state governments both share power over industrial hemp regulation. However, the Farm Bill also provided the FDA with authority to regulate cannabis and hemp-derived products.
Fatty acids are vital parts of the fat-soluble components of living cells (lipids).
Flavonoids within the cannabis and hemp plant are the polyphenolic compounds that give the plant its aroma and color.
As a result of its versatility, flower is the most popular form of cannabis.
The FDA officially approved the CBD product Epidiolex, which is a remedy for epilepsy. Today, the FDA’s relationship with cannabis and CBD brands is constantly evolving. Learn more about how the FDA is handling the cannabis and CBD industry by visiting the FDA’s website.
The list of cannabinoids includes cannabidiol (CBD), cannabinol (CBN), and cannabigerol (CBG).
Full-Spectrum CBD products also have other naturally-occurring chemical compounds derived from the hemp plant, such as terpenes, flavonoids, fatty acids, and essential oils. For a full-spectrum CBD remedy to be federally legal within the United States, it must contain less than .3% tetrahydrocannabinol (THC).
Manufacturers typically make CBD gummies using ingredients like cannabidiol (CBD) oil, sugar, corn syrup, water, citric acid, gelatin, and flavoring. Similar to other candies, CBD gummies come in a wide array of styles and flavors.
Manufacturers use the hemp plant to develop CBD products, which must include less than .3% of THC.
Homogeneity also refers to testing for even distribution of CBD or THC in a product.
Other materials, including sand, gravel, or water, can replace the dirt.
Under the 2018 Farm Bill, all hemp-derived products are legal in the U.S. if they contain less than .3% THC.
Isolate doesn’t feature any other cannabinoids or compounds, like terpenes, flavonoids, essential oils, or fatty acids.
CBD lotions are great for various conditions, such as acne, dry skin, and inflammation.
These plants produce flowers that contain phytocannabinoids. People use phytocannabinoids for their medicinal and psychoactive properties.
Users may find that microdosing is beneficial because it allows the body to maintain stable levels of CBD around the clock. For those who take CBD for its balancing properties, this consistency can be crucial.
Non-psychotoxic products will not produce a negative impact on the mind, personality, or behavior.
Nutraceuticals feature nutrients that manufacturers derive from food products, and they are typically concentrated in a powder, liquid, capsule, or pill form.
These farming methods boost the health of the environment and the consumer. Typically, organic remedies appeal to consumers who support sustainable farming practices and want to use safe, quality products.
Our organic CBD products include 100% certified organic hemp. However, at this time, the USDA is only certifying farms that grow organic hemp, not CBD products.
Research indicates that CBD for pets may help relieve several conditions, including separation fear, anxiety, joint pain, seizures, ear issues, gastrointestinal problems, muscle pain, and nausea.
There are many phytocannabinoids, including CBD, CBG, CBN, and THC. However, each phytocannabinoid delivers its own unique therapeutic effects on the body.
Potency is typically used in the context of drugs and medications in reference to how strong they are or can become.
Propylene glycol (PG) is typically used with vegetable glycerin (VG).
A psychoactive ingredient can alter a person’s mood, perception, consciousness, behavior, or cognition. In cannabis strains, THC is the primary psychoactive component.
Within the context of cannabis, it relates to the “high” that’s often associated with the recreational use of marijuana.
This oil contains a substance called cannabidiolic acid (CBDA) in addition to CBD. Manufacturers must heat the raw CBD oil to remove any traces of CBDA.
Examples of major retailers include CVS Health, Walgreens, and Rite Aid. Today, many retailers are selling CBD products.
Extracting rosin from the cannabis plant requires manufacturers to place the raw plant material between two heated plates that administer high pressure. This process then leads to a dense, thick, and sappy-type substance called rosin.
Examples include oral administration like CBD capsules and topical application like CBD creams.
CBD rubs can be thick liquids, such as creams or solid sticks that users apply to their skin.
These remedies must be applied directly to the skin.
Unlike Cannabis indica, sativa strains provide a more energetic, uplifting, and euphoric feeling.
With CBD serums, users must apply the remedy directly to the surface of their skin.
These remedies usually consist of dissolvable gelatin containers that feature the nutrients that users should consume.
For example, industrial hemp is a strain that includes high levels of CBD and trace amounts of THC, making it legal under the 2018 Farm Bill and useful for medicinal purposes.
With a sublingual, users must place the formula underneath their tongue for a certain amount of time. While the CBD substance is there, it absorbs into the bloodstream through the mucus membrane to create a therapeutic effect.
These products are alternatives to marijuana. However, the Centers for Disease Control and Prevention (CDC) warns that the effects of synthetic cannabis are unpredictable, harmful, and significantly different from those of marijuana.
Researchers believe that more than 20,000 terpenes exist and that cannabis has more than 100 terpenes. Every cannabis strain has its own terpene profile. When combined with other compounds, the effects of any given terpene may amplify.
THC is a cannabinoid in cannabis that produces a psychoactive effect when present in high amounts.
This cannabis compound is a non-psychoactive cannabinoid found in live and raw cannabis. When the plant dries, THCA starts to slowly convert to THC, but applying heat can speeds up this process. Research on THCA is still in its infancy, but studies suggest that THCA may have anti-inflammatory, anti-proliferative, antiemetic, and neuroprotective properties.
This compound is found in cannabis, but most strains contain trace amounts of THCV. While research is still in progress, studies suggest that THCV may suppress appetite, reduce panic attacks, stimulate bone growth, boost heart health, and help with Alzheimer’s.
This molecule is the precursor to tetrahydrocannabivarin (THCV).
This administration method can contain other substances such as alcohol, MCT oil, coconut oil, glycerin, and flavoring. CBD tinctures are available as full-spectrum, broad-spectrum, and isolate CBD products. They are often taken under the tongue for maximum effect, but users can also mix CBD tinctures with beverages.
These remedies are available in many forms, including masks, salves, balms, serums, and lotions. Typically, people use topical CBD for joint pain, muscle pain, dry skin, acne, and various other conditions.
Usually referred to as CBD vape oil, CBD vape juice is heated within a tank and is vaporized before users inhale it into their lungs.
CBD vape pens are available in both reusable and disposable variations. When the CBD vape juice is heated and vaporized, users can inhale it into their lungs.
Vaporizers can work with dried cannabis, cannabis oil, cannabis wax, or CBD oil.
For example, some CBD companies own the farms that grow their hemp, the barns that store their hemp, and the labs that test their hemp. By owning the entire supply chain, a vertically integrated business can ensure better quality control and maintain its core values and practices across every part of the production process.